Isolation and X-ray structure of deoxycholic acid from the sponge Ircinia sp.
نویسندگان
چکیده
Ethyl acetate extract of the sponge Ircinia sp., collected by SCUBA divers off the coast of southern India, contained a cholest-based sterol of insignificant antimicrobial activity, with one carboxylic acid side chain (3alpha, 7beta-dihydroxy-5beta-cholan-24-oic acid, DCA). The structure of the compound was determined by spectroscopic data and single crystal X-ray diffraction studies. DCA crystallizes in the tetragonal space group P4(1)2(1)2, chirality documented by solution optical rotation [alpha]D = +67.4 degrees (c 0.16, CHCl3).
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عنوان ژورنال:
- Natural product communications
دوره 6 9 شماره
صفحات -
تاریخ انتشار 2011